I hate asymmetric bowling balls. I have never had a single one that reacted well for me, but I am rolling the ball much better these days, and decided it was time to once again try to put an asymmetric piece in my bag to get a different look than what I have now. (I'm a lefty by the way, can you tell fomr the name?)...
I recently threw a friend's highly touted new asymmetric release (he's right handed). I will not name the ball, because this question has nothing to do with the ball itself, seriously. Every asymmetric I have ever thrown does exactly the same thing: it lopes down the lane, makes a labored turn, and refuses to drive through the pins. I have also been told that asymmetric balls are picky, and must be drilled correctly. That was in the same conversation where I was guaranteed that using an asymmetric right handed ball would yield a valid assessment, although not perfect.
My PAP is 5x1.5 up. This ball was drilled right handed, ping over ring and MB 1 inch to the right of the thumb.
The ball, predictably, puked and puked badly. It looked EXACTLY like every asym I've ever thrown. The question I need ask is this: either throwing a right-handed asymmetric ball for a left-hander is totally ridiculous and the test is completely invalid, even though it reacted just like every other asymmetric I have ever thrown, or it is true that I should have been able to get a decent read on the ball, which puts us back into the I don't like asymmetric category.
I realize this question is a bit circuitous and I hope it makes appropriate sense, but can I trust this test or not?
Feedback appreciated as always.

What I have noticed when rolling asymmetricals; is that they want to roll more forward at the breakpoint whereas symmetricals can go more sideways depending on the rg and diff numbers.  Asymmetricals for me tend to work best when the lanes are playing tight and I can square up in the track area.  I always have issues with continuation playing deeper than 18-20 at the arrows.  The balls lack entry angle and I wrap ten pins more than Christmas presents in December.

The fact you took a ball probably pin of 6.5 inches from your PAP and a horrible mass bias placement for you I am sure had everything to do with the ball rolling like a turd. 

What I would suggest.....is if you wanted to try an asymmetrical again; get one with a low intermediate differential because you can drill the ball with a symmetrical layout and be fine.  Find a ball with an intermediate diff of less than .008.  Once you get to .010 and higher, thats when I see the ball roll more forward at the breakpoint and not so much sideways.

Yes, almost everything I have is symmetric with a flare increasing hole around P3-P4. Pin is usually above ring or in the middle, with Cg kicked out at 45 minimum.

I don't know if this does anything for you, but my Sinister rolls better for me than any ball ever has when I throw right handed. If I throw it left handed (roughly same specs, only flipped, it rolls like doggy turds. It rolls even worse if I throw a backup ball

+1

I hate asymmetric bowling balls.

You have obviously have never had one drilled correctly for your PAP, rev rate, ball speed, with the correct surface for the oil conditions on which you ar bowling. Yes, they are trickier to drill than symmetrics, but they are not impossible. Someone ss doing you wrong, if you haven't found a good reaction for you. Because yo usually use stronger balls, asymmetrics are made for you.

I recently threw a friend's highly touted new asymmetric release (he's right handed). I will not name the ball, because this question has nothing to do with the ball itself, seriously. Every asymmetric I have ever thrown does exactly the same thing: it lopes down the lane, makes a labored turn, and refuses to drive through the pins. I have also been told that asymmetric balls are picky,

They are not picky; they just need more and SPECIFIC bowler's delivery information before they can be drilled properly. Its science, not magic. I repeat, it is science, knowledge and little bit craft an tiny bit iof imagination. BUT it is NOT rocket science.

and must be drilled correctly. That was in the same conversation where I was guaranteed that using an asymmetric right handed ball would yield a valid assessment, although not perfect.

Horse manure! Whoever told you that is a Snake-oil salesman or your enemy or an ignoramus. But he ain't a driller.

My PAP is 5x1.5 up. This ball was drilled right handed, ping over ring and MB 1 inch to the right of the thumb.

Ok, time for clarification since no one else here asked for it; I will:
Was it pin over YOUR ring or over the righty's ring?
Was it MB 1" right of his thumb or your thumb?

Without this info, you're talking about a "pig in a poke".

The ball, predictably, puked and puked badly. It looked EXACTLY like every asym I've ever thrown. The question I need ask is this: either throwing a right-handed asymmetric ball for a left-hander is totally ridiculous and the test is completely invalid, even though it reacted just like every other asymmetric I have ever thrown, or it is true that I should have been able to get a decent read on the ball, which puts us back into the I don't like asymmetric category.
I realize this question is a bit circuitous and I hope it makes appropriate sense, but can I trust this test or not?
Feedback appreciated as always.

Your PAP of 1.5" up "USUALLY" indicates a spinner type of release.  An acquaintance of many years ago had a PAP like that and he had many screwed up drillings that 17 different drillers gave hm. I am no driller, but have had some experience diagnosing different drillings, especially bad ones on asymmetric cored balls.
(I really, really wish one or more of our experienced drillers would be doing this; but if no one steps up and helps Lefty, I'll do my best.)

FYI In general, asymmetrics can be drilled to do almost anything, if drilled correctly. They can be flippy or very controlled. There is no "every asymmetric is always controlled for me". If so, your driller is still not doing it right. Once drilled for one type of reaction, most asymmetrics will not be forced into changing its reaction due to hand release changes or ball speed changes. Symmetrics, once drilled, can be made to change their reaction by hand changes and speed changes. That is a major difference in these cores.
PLUS Asymmetrics are best used by people, who are on the more consistent side with respect to speed and release.

You're a lefty, but the ball was laid out for a righty?  If I understand the situation (I've read quickly) then INVALID test in my opinion.

Yes, it was laid out for a righty. Looking at it as a RIGHT handed layout it was pin just over ring and MB approx 1 inch right of thumb.

 
For a righty (and the lefty equivalent), the drill you described above is a fairly "standard" asymmetric drill. It's a safe pattern and works well for a wide range of bowlers. You'll see rough approximations of that pattern (pin between the center grip line and ring, MB in the strong position) on the majority of asymmetric balls on the racks.   
 
If you've had that pattern on any of your previous asymmetric balls, and you couldn't get at least a decent reaction, there is something going on with your release that needs to be assessed in person. Has anyone ever provided an in person assessment to you?